@article{22216, author = {Yadav A. and Kumar V. and Modi G. and Jha V. and John O. and Prasad N. and Gang S. and Ojha J. and Pandey R. and Parameswaran S. and Sahay M. and Varughese S.}, title = {The Indian Chronic Kidney Disease (ICKD) Study: Design and Methods}, abstract = {

BACKGROUND: The rate and factors that influence progression of chronic kidney disease (CKD) in developing countries like India are unknown. A pan-country prospective, observational cohort study is needed to address these knowledge gaps. METHODS: The Indian Chronic Kidney Disease (ICKD) study will be a cohort study of approximately 5000 patients with mild to moderate CKD presenting to centers that represent different geographical regions in India. Time to 50% decline in baseline estimated glomerular filtration rate, need of renal replacement therapy or any new cardiovascular disease (CVD) event or death from CVD are the primary end points. VALUE OF STUDY: This study will provide the opportunity to determine risk factors for CKD progression and development of CVD in Indian subjects and perform international comparisons to determine ethnic and geographical differences. A bio-repository will provide a chance to discover biomarkers and explore genetic risk factors.

}, year = {2016}, journal = {Nephrology (Carlton)}, edition = {2016/04/12}, month = {169456852783}, isbn = {1440-1797 (Electronic)
1320-5358 (Linking)}, note = {Kumar, Vivek
Yadav, Ashok Kumar
Gang, Sishir
John, Oommen
Modi, Gopesh K
Ojha, Jai Prakash
Pandey, Rajendra
Parameswaran, Sreejith
Prasad, Narayan
Sahay, Manisha
Varughese, Santosh
Jha, Vivekanand
Nephrology (Carlton). 2016 Apr 6. doi: 10.1111/nep.12789.}, language = {Eng}, }