TY - JOUR AU - Correa-Rotter R. AU - Jha V. AU - Burdmann E. AU - Glaser J. AU - Lemery J. AU - Rajagopalan B. AU - Diaz H. AU - Garcia-Trabanino R. AU - Taduri G. AU - Madero M. AU - Amarasinghe M. AU - Abraham G. AU - Anutrakulchai S. AU - Stenvinkel P. AU - Roncal-Jimenez C. AU - Lanaspa M. AU - Sheikh-Hamad D. AU - Andres-Hernando A. AU - Milagres T. AU - Weiss I. AU - Kanbay M. AU - Wesseling C. AU - Sanchez-Lozada L. AU - Johnson R. AB -

Climate change has led to significant rise of 0.8 degrees C-0.9 degrees C in global mean temperature over the last century and has been linked with significant increases in the frequency and severity of heat waves (extreme heat events). Climate change has also been increasingly connected to detrimental human health. One of the consequences of climate-related extreme heat exposure is dehydration and volume loss, leading to acute mortality from exacerbations of pre-existing chronic disease, as well as from outright heat exhaustion and heat stroke. Recent studies have also shown that recurrent heat exposure with physical exertion and inadequate hydration can lead to CKD that is distinct from that caused by diabetes, hypertension, or GN. Epidemics of CKD consistent with heat stress nephropathy are now occurring across the world. Here, we describe this disease, discuss the locations where it appears to be manifesting, link it with increasing temperatures, and discuss ongoing attempts to prevent the disease. Heat stress nephropathy may represent one of the first epidemics due to global warming. Government, industry, and health policy makers in the impacted regions should place greater emphasis on occupational and community interventions.

AD - Due to the number of contributing authors, the affiliations are provided in the Supplemental Material.
Due to the number of contributing authors, the affiliations are provided in the Supplemental Material. Richard.Johnson@ucdenver.edu. AN - 27151892 BT - Clinical Journal of the American Society of Nephrology DP - NLM ET - 2016/05/07 LA - Eng LB - UK
INDIA
FY16 N1 - Glaser, Jason
Lemery, Jay
Rajagopalan, Balaji
Diaz, Henry F
Garcia-Trabanino, Ramon
Taduri, Gangadhar
Madero, Magdalena
Amarasinghe, Mala
Abraham, Georgi
Anutrakulchai, Sirirat
Jha, Vivekanand
Stenvinkel, Peter
Roncal-Jimenez, Carlos
Lanaspa, Miguel A
Correa-Rotter, Ricardo
Sheikh-Hamad, David
Burdmann, Emmanuel A
Andres-Hernando, Ana
Milagres, Tamara
Weiss, Ilana
Kanbay, Mehmet
Wesseling, Catharina
Sanchez-Lozada, Laura Gabriela
Johnson, Richard J
Clin J Am Soc Nephrol. 2016 May 5. pii: CJN.13841215. N2 -

Climate change has led to significant rise of 0.8 degrees C-0.9 degrees C in global mean temperature over the last century and has been linked with significant increases in the frequency and severity of heat waves (extreme heat events). Climate change has also been increasingly connected to detrimental human health. One of the consequences of climate-related extreme heat exposure is dehydration and volume loss, leading to acute mortality from exacerbations of pre-existing chronic disease, as well as from outright heat exhaustion and heat stroke. Recent studies have also shown that recurrent heat exposure with physical exertion and inadequate hydration can lead to CKD that is distinct from that caused by diabetes, hypertension, or GN. Epidemics of CKD consistent with heat stress nephropathy are now occurring across the world. Here, we describe this disease, discuss the locations where it appears to be manifesting, link it with increasing temperatures, and discuss ongoing attempts to prevent the disease. Heat stress nephropathy may represent one of the first epidemics due to global warming. Government, industry, and health policy makers in the impacted regions should place greater emphasis on occupational and community interventions.

PY - 2016 SN - 1555-905X (Electronic)
1555-9041 (Linking) T2 - Clinical Journal of the American Society of Nephrology TI - Climate Change and the Emergent Epidemic of CKD from Heat Stress in Rural Communities: The Case for Heat Stress Nephropathy Y2 - FY16 ER -