TY - JOUR
AU - Yadav A.
AU - Kumar V.
AU - Modi G.
AU - Jha V.
AU - John O.
AU - Prasad N.
AU - Gang S.
AU - Ojha J.
AU - Pandey R.
AU - Parameswaran S.
AU - Sahay M.
AU - Varughese S.
AB - <p>
BACKGROUND: The rate and factors that influence progression of chronic kidney disease (CKD) in developing countries like India are unknown. A pan-country prospective, observational cohort study is needed to address these knowledge gaps. METHODS: The Indian Chronic Kidney Disease (ICKD) study will be a cohort study of approximately 5000 patients with mild to moderate CKD presenting to centers that represent different geographical regions in India. Time to 50% decline in baseline estimated glomerular filtration rate, need of renal replacement therapy or any new cardiovascular disease (CVD) event or death from CVD are the primary end points. VALUE OF STUDY: This study will provide the opportunity to determine risk factors for CKD progression and development of CVD in Indian subjects and perform international comparisons to determine ethnic and geographical differences. A bio-repository will provide a chance to discover biomarkers and explore genetic risk factors.
</p>

AD - Department of Nephrology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.<br/>Muljibhai Patel Urological Hospital, Nadiad, India.<br/>George Institute for Global Health, New Delhi, India.<br/>Samarpan Kidney Institute and Research Center, Bhopal, India.<br/>Department of Nephrology, Institute of Medical Science, Banaras Hindu University, Varanasi, India.<br/>Department of Nephrology, Institute of Post Graduate Medical Education & Research, Kolkata, India.<br/>Department of Nephrology, Jawaharlal Institute of Postgraduate Medical Education & Research, Pondicherry, India.<br/>Department of Nephrology, Sanjay Gandhi Postgraduate Institute of Medical Science, Lucknow, India.<br/>Department of Nephrology, Osmania Medical College, Osmania General Hospital, Hyderabad, India.<br/>Department of Nephrology, Christian Medical College, Vellore, India.<br/>University of Oxford, Oxford, UK.
AN - 27062078
BT - Nephrology (Carlton)
DA - 169456852783
DP - NLM
ET - 2016/04/12
LA - Eng
LB - UK<br/>INDIA<br/>FY16
N1 - Kumar, Vivek<br/>Yadav, Ashok Kumar<br/>Gang, Sishir<br/>John, Oommen<br/>Modi, Gopesh K<br/>Ojha, Jai Prakash<br/>Pandey, Rajendra<br/>Parameswaran, Sreejith<br/>Prasad, Narayan<br/>Sahay, Manisha<br/>Varughese, Santosh<br/>Jha, Vivekanand<br/>Nephrology (Carlton). 2016 Apr 6. doi: 10.1111/nep.12789.
N2 - <p>
BACKGROUND: The rate and factors that influence progression of chronic kidney disease (CKD) in developing countries like India are unknown. A pan-country prospective, observational cohort study is needed to address these knowledge gaps. METHODS: The Indian Chronic Kidney Disease (ICKD) study will be a cohort study of approximately 5000 patients with mild to moderate CKD presenting to centers that represent different geographical regions in India. Time to 50% decline in baseline estimated glomerular filtration rate, need of renal replacement therapy or any new cardiovascular disease (CVD) event or death from CVD are the primary end points. VALUE OF STUDY: This study will provide the opportunity to determine risk factors for CKD progression and development of CVD in Indian subjects and perform international comparisons to determine ethnic and geographical differences. A bio-repository will provide a chance to discover biomarkers and explore genetic risk factors.
</p>

PY - 2016
SN - 1440-1797 (Electronic)<br/>1320-5358 (Linking)
T2 - Nephrology (Carlton)
TI - The Indian Chronic Kidney Disease (ICKD) Study: Design and Methods
Y2 - FY16
ER -