Advanced Trauma life support

Effects of Advanced Trauma Life Support® training compared to standard care on adult trauma patient outcomes

Background

  • Most deaths from trauma occur within the first 24-48 hours. Most preventable trauma deaths are caused by clinical judgement errors during initial resuscitation or early care, including airway management and haemorrhage control.
  • The proprietary Advanced Trauma Life Support® (ATLS®) is the most established trauma life support training program.

Aims

Compare the effects of ATLS® training with standard care on outcomes in adult trauma patients in low- and middle-income countries (LMICs), including recovery before discharge and functional outcomes at and after discharge such as pain, mobility and self-care activities.

Methods

  • This is a stepped-wedge cluster randomised trial. All clusters (hospitals) will transition through three phases: a standard care phase; transition phase during which the training is delivered; and an intervention phase. 
  • Adult trauma patients presenting to the emergency departments of 30 hospitals will be recruited for the study. The total sample size will include 4,320 patients across these hospitals.

Impacts

  • Due to its large sample size and geographical representativeness, the study will produce robust evidence comparing ATLS® training to standard care in adult trauma patients, which will enhance our understanding and inform best practices in trauma care. 
  • Evidence from this study could influence healthcare guidelines and lead to improvements and updates in the training curriculum, enhancing its effectiveness in LMICs. 
  • By its design and implementation, this study could improve the early management of trauma patients in participating hospitals by providing a structured framework for assessment and treatment.

Current status

The study has been registered into CTRI. Currently study is in pre-initiation phase.

Principal Investigator

Dr Martin Gerdin Wärnberg

Regional Coordinating Centre-Chief Investigator  

Dr. Nobhojit Roy

Prof. Vivekanand Jha

Partners

The George Institute for Global Health 

Karolinska Institutet 

Funders 

The George Institute for Global Health 

Swedish Research Council 

Related resources

Further reading