Innovative clinical trial design
We are driving innovative clinical trial designs and ensuring our research is efficient and allows quick translation to practice. This includes cluster trials (for example, our HeadPoSt trial - a cluster of crossover trials of head positioning after stroke), and our Consumer Navigation of Electronic Cardiovascular Tools study (Connect)
We are currently exploring opportunities for use of adaptive designs and platform trials. The idea is to be able to adjust the design of a trial as new information accumulates. This might include adjusting the recruitment to maximise the number of patients allocated to the most promising therapy or assessing multiple potential treatments in a single ongoing trial.